Saturday, February 4, 2012

Russia, China veto UN resolution on Syria

This image from amateur video made available by Shaam News Network on Saturday, Feb. 4, 2012, purports to show a wounded man being treated at a field hospital in Homs, Syria. Syrian forces unleashed a barrage of mortars and artillery on the battered city of Homs for hours before dawn on Saturday, sending terrified residents fleeing into basements and killing scores of people in what appeared to be the bloodiest episode in the nearly 11-month-old uprising, activists said.(AP Photo/Shaam News Network via APTN) THE ASSOCIATED PRESS CANNOT INDEPENDENTLY VERIFY THE CONTENT, DATE, LOCATION OR AUTHENTICITY OF THIS MATERIAL. TV OUT

This image from amateur video made available by Shaam News Network on Saturday, Feb. 4, 2012, purports to show a wounded man being treated at a field hospital in Homs, Syria. Syrian forces unleashed a barrage of mortars and artillery on the battered city of Homs for hours before dawn on Saturday, sending terrified residents fleeing into basements and killing scores of people in what appeared to be the bloodiest episode in the nearly 11-month-old uprising, activists said.(AP Photo/Shaam News Network via APTN) THE ASSOCIATED PRESS CANNOT INDEPENDENTLY VERIFY THE CONTENT, DATE, LOCATION OR AUTHENTICITY OF THIS MATERIAL. TV OUT

This image from amateur video made available by Shaam News Network on Saturday, Feb. 4, 2012, purports to show a wounded man being treated at a field hospital in Homs, Syria. Syrian forces unleashed a barrage of mortars and artillery on the battered city of Homs for hours before dawn on Saturday, sending terrified residents fleeing into basements and killing scores of people in what appeared to be the bloodiest episode in the nearly 11-month-old uprising, activists said.(AP Photo/Shaam News Network via APTN) THE ASSOCIATED PRESS CANNOT INDEPENDENTLY VERIFY THE CONTENT, DATE, LOCATION OR AUTHENTICITY OF THIS MATERIAL. TV OUT

Portuguese representative Jose Filipe Moraes Cabral, left, and South African representative Baso Sangqu, right, glance at Russian representative Vitaly Churkin, center, as they vote in support of a draft resolution backing an Arab League call for Syrian President Bashar Assad to step down, which was later vetoed by Russia and China, during a meeting of the United Nations Security Council at United Nations headquarters on Saturday, Feb. 4, 2012. The unusual weekend session comes as Syrian forces pummel the city of Homs with mortars and artillery in what activists are calling one of the bloodiest episodes of the uprising. (AP Photo/Jason DeCrow)

Syrian representative Bashar Ja'afari listens during a meeting of the United Nations Security Council at United Nations headquarters Saturday, Feb. 4, 2012. During the meeting, Russia and China vetoed a Security Council resolution backing an Arab League peace plan that calls for Syrian President Bashar Assad to step down. The unusual weekend session comes as Syrian forces pummel the city of Homs with mortars and artillery in what activists are calling one of the bloodiest episodes of the uprising. (AP Photo/Jason DeCrow)

From left, French representative Gerard Araud, British representative Mark Lyall Grant and U.S. representative Susan Rice confer before a meeting of the United Nations Security Council at United Nations headquarters on Saturday, Feb. 4, 2012. The unusual weekend session comes as Syrian forces pummel the city of Homs with mortars and artillery in what activists are calling one of the bloodiest episodes of the uprising. During the meeting, Russia and China vetoed a Security Council resolution backing an Arab League peace plan that calls for Syrian President Bashar Assad to step down. (AP Photo/Jason DeCrow)

(AP) ? Russia and China vetoed a U.N. Security Council resolution backing calls for Syrian President Bashar Assad to step down, despite international outrage Saturday over a devastating bombardment of the city of Homs by his regime's forces. Activists said more than 200 were killed in the bloodiest episode of the nearly 11-month uprising.

The overnight onslaught on restive neighborhoods in Homs, Syria's third largest city, signaled a willingness by Assad's regime to bring a new level of violence to stamp out an opposition that has grown increasingly bold and armed.

Its timing, hours before a planned vote on the U.N. resolution, suggested Assad was confident of his ally Russia's protection on the world stage.

Residents of Homs on Saturday described a night of ceaseless bombardment by mortars and rockets that lasted until dawn, sending them fleeing to lower floors and basements. When daylight came, dozens of buildings were left punctured by shells, facades collapsed, and some streets were stained with blood.

Thousands gathered for a funeral ceremony for some of the victims in the worst hit neighborhood, Khaldiyeh, where more than 60 coffins and bodies in white shrouds were lined up in a park, according to footage of the scene.

"A few more nights like this one and Homs will be erased from the map," Ammar, a resident, said, speaking on condition that only his first name be used for fear he and his family could be targeted. "We are being massacred."

Activists' reports of the death toll could not be independently confirmed, and the counts varied due to the confusion of tracking the dead.

The Syrian government denied any bombardment took place at all, saying the high death tolls were opposition propaganda aimed at pressuring the United Nations and the bodies were those of people who had been kidnapped previously by "terrorists."

The bloodshed added heat to negotiations that have been going on for days, as Western and Arab nations tried to overcome Russia's opposition to the resolution. The measure would have backed an Arab call for Assad to hand over his powers to his vice president and allow formation of a unity government.

"The Assad regime must come to an end," President Barack Obama said in a statement Saturday before the vote, calling on the Security Council to "stand against the Assad regime's relentless brutality."

But Russia demanded further changes be made, saying the draft did not make enough demands on the armed opposition in Syria and calls for Assad to step aside could wreck chances for a negotiated solution to the country's upheaval. In the end, the resolution's proponents pushed ahead with a vote, challenging Moscow to veto or back down.

After the veto, U.S. Ambassador Susan Rice said her country was "disgusted" by the vote.

"It is a sad day for this council, a sad day for Syrians and a sad day for all friends of democracy," French Ambassador Gerard Araud said. He said Russia and China had "made themselves complicit in a policy of repression carried out by the Assad regime."

Syria has been a key Russian ally since Soviet times and Moscow has opposed any U.N. call that could be interpreted as advocating military intervention or regime change. Russia and China also used their veto powers as permanent council members in October to block a previous Western attempt to condemn the violence in Syria.

Assad has seen the Russian backing as crucial as he wages a crackdown that has killed well over 5,400 people since March, according to a U.N. estimate.

In a sign of Assad's thinking, a pro-Syrian Lebanese politician who met with the Syrian leader last week told a Lebanese newspaper that Assad was "confident in the Russian position."

Wiam Wahhab said Assad told him that the time had come to decisively put an end to the uprising. "The price of chaos is worse than the price of decisiveness," he quoted Assad as telling him.

The regime has appeared more determined to crush army defectors who have joined the uprising and grown increasingly bold, trying to overtly establish control of pro-opposition cities and neighborhoods. Last week, regime forces carried out a heavy offensive to crush defectors who held sway in suburbs of Damascus, bringing them to the doorstep of the capital.

There were signs that the bombardment in Homs was in response to moves by army defectors to solidify control in several neighborhoods.

Residents reported that defectors set up new checkpoints in several areas, and two Homs activists said defectors attacked a military checkpoint in the Khaldiyeh district Thursday night, capturing 17 soldiers. The activists spoke on condition of anonymity to protect themselves from retaliation.

On Saturday, thousands protested across Syria in solidarity with the beleaguered city. "Homs, your blood will not go in vain," read a banner held by a protester a Damascus suburb.

At least 21 people were killed in violence outside Homs on Saturday, including 12 shot when security forces opened fire on a funeral procession for victims of a shooting in the Damascus suburb of Daraya a day earlier, according to the British-based Syrian Observatory for Human Rights.

Tunisia decided to expel Syria's ambassador and end its recognition of Assad's regime in response to what it called a "bloody massacre" in Homs. Angry Syrians stormed their embassies in Berlin, London, Athens, Cairo and Kuwait, clashing with guards and police and ? in Cairo ? setting fire to part of the embassy.

In Khaldiyeh, an overwhelmingly Sunni Muslim district of Homs, residents checked on relatives after a night spent in hiding and cleaned streets of shattered glass, debris and bloodstains. As many as 30 buildings were left uninhabitable by the extent of the damage, said local activist Majd Amer.

Mohammad, a Khaldiyeh resident who like most in Homs declined to be further identified, said the shelling started shortly before midnight and lasted until early Saturday.

"We were sitting at home and the mortars just started slamming into buildings around us," he said by telephone. "There was nothing that prompted it, not even protests ... people are terrified today."

"It's a catastrophe, no other way to describe it," he said.

Online video by activists taken during the onslaught showed chaotic scenes in a makeshift clinic set up in what appeared to be a Khaldiyeh mosque, the room filled with wounded men with gashes and broken limbs being bandaged as well as several dead bodies. In another video, fire ravaged a house that had been shelled, as people poured water on the blaze.

The videos could not be independently verified.

The Syrian Observatory said the death toll in Homs was at least 217, counting victims whose names it had collected. About 140 of the deaths were in Khaldiyeh, it said. The Syrian National Council, one of the main opposition groups, put the toll at more than 220.

"This is the worst attack of the uprising, since the uprising began in March until now," said Rami Abdul-Rahman, the head of the Observatory, which tracks violence through contacts on the ground.

The group's figures could not be independently verified.

Residents said most shelling came from a military installation west of Khaldiyeh and Alawite-dominated neighborhoods to the east. Syria's Alawite minority, which belongs to an offshoot of Shiite Islam, forms the backbone of Assad's regime and the military leadership.

Homs has been one of the biggest centers of anti-regime protests since March and has seen increasingly large numbers of army defectors. It has been hit by near daily regime raids and fighting. It has also seen bloody bouts of tit-for-tat killings between its Alawite and Sunni communities, a harbinger of what many Syrians fear could happen if the country descends into an outright confrontation of armed forces.

Syria's uprising began with peaceful protests around the country. But in the face of the regime's withering crackdown, the opposition has increasingly taken up arms. Military and security forces have responded with progressively greater force.

___

Snow reported from the United Nations. Associated Press writers Aya Batrawy in Cairo and Bouazza ben Bouazza in Tunis contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2012-02-04-ML-Syria/id-250729944590444cb673ae9295306c8d

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Friday, February 3, 2012

Discovery of extremely long-lived proteins may provide insight into cell aging and neurodegenerative diseases

ScienceDaily (Feb. 3, 2012) ? One of the big mysteries in biology is why cells age. Now scientists at the Salk Institute for Biological Studies report that they have discovered a weakness in a component of brain cells that may explain how the aging process occurs in the brain.

The scientists discovered that certain proteins, called extremely long-lived proteins (ELLPs), which are found on the surface of the nucleus of neurons, have a remarkably long lifespan.

While the lifespan of most proteins totals two days or less, the Salk Institute researchers identified ELLPs in the rat brain that were as old as the organism, a finding they reported February 3 in Science.

The Salk scientists are the first to discover an essential intracellular machine whose components include proteins of this age. Their results suggest the proteins last an entire lifetime, without being replaced.

ELLPs make up the transport channels on the surface of the nucleus; gates that control what materials enter and exit. Their long lifespan might be an advantage if not for the wear-and-tear that these proteins experience over time. Unlike other proteins in the body, ELLPs are not replaced when they incur aberrant chemical modifications and other damage.

Damage to the ELLPs weakens the ability of the three-dimensional transport channels that are composed of these proteins to safeguard the cell's nucleus from toxins, says Martin Hetzer, a professor in Salk's Molecular and Cell Biology Laboratory, who headed the research. These toxins may alter the cell's DNA and thereby the activity of genes, resulting in cellular aging.

Funded by the Ellison Medical Foundation and the Glenn Foundation for Medical Research, Hetzer's research group is the only lab in the world that is investigating the role of these transport channels, called the nuclear pore complex (NPC), in the aging process.

Previous studies have revealed that alterations in gene expression underlie the aging process. But, until the Hetzer lab's discovery that mammals' NPCs possess an Achilles' heel that allows DNA-damaging toxins to enter the nucleus, the scientific community has had few solid clues about how these gene alterations occur.

"The fundamental defining feature of aging is an overall decline in the functional capacity of various organs such as the heart and the brain," says Hetzer. "This decline results from deterioration of the homeostasis, or internal stability, within the constituent cells of those organs. Recent research in several laboratories has linked breakdown of protein homeostasis to declining cell function."

The results that Hetzer and his team just report suggest that declining neuron function may originate in ELLPs that deteriorate as a result of damage over time.

"Most cells, but not neurons, combat functional deterioration of their protein components through the process of protein turnover, in which the potentially impaired parts of the proteins are replaced with new functional copies," says Hetzer.

"Our results also suggest that nuclear pore deterioration might be a general aging mechanism leading to age-related defects in nuclear function, such as the loss of youthful gene expression programs," he adds.

The findings may prove relevant to understanding the molecular origins of aging and such neurodegenerative disorders as Alzheimer's disease and Parkinson's disease.

In previous studies, Hetzer and his team discovered large filaments in the nuclei of neurons of old mice and rats, whose origins they traced to the cytoplasm. Such filaments have been linked to various neurological disorders including Parkinson's disease. Whether the misplaced molecules are a cause, or a result, of the disease has not yet been determined.

Also in previous studies, Hetzer and his team documented age-dependent declines in the functioning of NPCs in the neurons of healthy aging rats, which are laboratory models of human biology.

Hetzer's team includes his colleagues at the Salk Institute as well as John Yates III, a professor in the Department of Chemical Physiology of The Scripps Research Institute.

When Hetzer decided three years ago to investigate whether the NPC plays a role in initiating or contributing to the onset of aging and certain neurodegenerative diseases, some members of the scientific community warned him that such a study was too bold and would be difficult and expensive to conduct. But Hetzer was determined despite the warnings.

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The above story is reprinted from materials provided by Salk Institute for Biological Studies, via Newswise.

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Journal Reference:

  1. J. N. Savas, B. H. Toyama, T. Xu, J. R. Yates, M. W. Hetzer. Extremely Long-Lived Nuclear Pore Proteins in the Rat Brain. Science, 2012; DOI: 10.1126/science.1217421

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/nHVpYXNxnbA/120203180905.htm

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3DS adds to its European WiFi arsenal, gains over 5,000 free hotspots

Like any new console, the 3DS has had its share of growing pains. But the awkward acne of its first year has mostly been smoothed over, giving way to an attractive price, a library of compelling content and even DLC freebies. So, what's left for the Big N to do? Well, over in Europe, the company's partnered up with free-hotspot.com giving, you guessed it, more gratis WiFi to owners across 21 different Euro zone countries. These 5,000 or so new access points will be made available at a variety of hotels and fast food chains throughout the continent. So, the next time you're lined up for a Royale with cheese, feel free to hop online and start working through that Netflix queue.

Continue reading 3DS adds to its European WiFi arsenal, gains over 5,000 free hotspots

3DS adds to its European WiFi arsenal, gains over 5,000 free hotspots originally appeared on Engadget on Thu, 02 Feb 2012 02:49:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/02/02/3ds-adds-to-its-european-wifi-arsenal-gains-over-5-000-free-hot/

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Thursday, February 2, 2012

Kingdom of Pets: Dog Training Special!

Kingdom of Pets will have your dog behave just the way you want him while giving you very clear picture of what ticks him off and what makes him happy. Man?s best friend is often misunderstood due to its inability to convey itself when feeling low or elated. Dogs are extremely intelligent creatures susceptible to mood swings and a number of other emotions. Their erratic behavior and difficulty in getting them trained is often a result of theirs master?s inability to decipher what their pet wishes. Kingdom of Pets helps you get in the mind of your dog and train it to not just become a part of your valuable family but impress your friends and families with how disciplined your dog is.

However, the entire system in based in experience and trial plus error module thus it?s not a concrete method. Dogs which may be suffering from diseases and other ailments may not respond to this program but that cannot reduce the effectiveness of Kingdom of Pets. Countless families have trained their beloved dogs to adapt a more domesticated life style and in return have forged themselves a family member no one can wish to let go of.

Why Is Kingdom Of Pets Going To Make A Great Dog Out Of Your Good Dog?

  • It has been tried and tested by 217,465 dog owners who have claimed its success. Finally a real program that can make your dog do everything you ever wished him to.
  • A six day course after which your dog will behave like the way a loving dog should and you would be perfectly okay leaving your favorite canine at home to guard without the fear of its antics.
  • Available in easy step by step eBook and video mode to help you understand better.
  • Amazing deal for $39.95.

And What You May Not Like About Kingdom Of Pets:

  • For meant to be applied to every dog. Teach a rabid stray at your own risk.
  • Some dogs have reportedly shown more aggression after applying these techniques.
  • Too pricey for a dog behaving guide.

Our Final Verdict On Kingdom Of Pets:

Worth a try. Never worry about your dog?s antics with Kingdom of Pets around. The guide is amazing, precise, informative and highly researched. For that alone it deserves a medal. Aside from that, Kingdom of Pets also handles a number of issues with your pet?s hygiene and health which makes it even more awesome.

Kingdom of Pets

Source: http://reviewout.com/kingdom-of-pets/

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News and Society Blog-Energy: Turning Down the Heat to Save ...

It is possible to help your budget and the environment at the same time. In fact, one very simple way to do just this is to just turn the heat down. Unlike other energy saving measures which require a significant investment of time and money, anyone can use this strategy from the individual at home to a big business.

At this point, you may well be sceptical!

Perhaps you are even wondering how low you may have to turn your thermostat in order to actually save energy and of course money. Well, the truth is that You will probably be pleasantly surprised to learn that you do not have to turn your heat down very much at all to see a savings in your energy bills.

According to studies done by The Carbon Trust, you could save up to 30% off your heating bills this winter by turning down your thermostat just 1 degree! In fact, if people and businesses across the country did just that, over 35 million pounds could be saved in energy and electricity bills. One degree of heat really amounts to a lot of money! Perhaps you might even try turning down the thermostat a whole 2 degrees in order to help save even more money and electricity and give some love back to the environment.

It won't make life uncomfortable

Lowering your heat one or two degrees should not make that much of a difference, if any, in your overall comfort this winter. In fact, your home or business may not even feel any colder to you even though the thermostat is set lower. If you are slightly uncomfortable due to the change in temperature, you can compensate by wearing a sweater or even some thermal underwear! You may also want to try dressing in layers to keep yourself warmer.

It is also important to not overheat your home or office as this can drive up your costs as well. In fact, overheating can raise your energy bills by around 8%. Keep in mind that you should slowly heat up a cold room. Turning up the heating thermostat as far as it can go in order to quickly heat a room does nothing more than wastes energy. It may be necessary to have an office staff meeting or discuss these tips with your family to ensure that everyone at your office or home is working towards lowering energy bills. Business electricity prices and consumer prices won't get cheaper at this time of year, so it is worth being conscientious.

Knowing that you are helping the environment should warm your heart a little bit and keep you motivated. However, the real motivation for your family might be the fact that there will be extra money in the budget to spend!

Graeme is writing on behalf of Haven Power - Business Electricity & Business Energy Solutions

Article Source:http://EzineArticles.com/?expert

Source: http://newsandsocietyblog-energy.blogspot.com/2012/02/turning-down-heat-to-save-energy-and.html

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Wednesday, February 1, 2012

I Don?t Care About Your Invisible Jeebus (Balloon Juice)

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Mozambique storm death toll reaches 32 people (AP)

MAPUTO, Mozambique ? Mozambique's chief disaster management official says 32 people have died in recent storms and flooding.

Joao Ribeiro, director of the National Disasters Management Institute, gave the toll to reporters in Maputo Tuesday. He also says thousands remained stranded by high waters across southern and central Mozambique.

Two tropical depressions that have hit since mid-January have brought heavy rains and high winds. Some victims have drowned, and others have been electrocuted by downed power lines.

Source: http://us.rd.yahoo.com/dailynews/rss/africa/*http%3A//news.yahoo.com/s/ap/20120131/ap_on_re_af/af_mozambique_floods

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